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Re: Parkinson's Linked to Residential Pesticide Use


Does this mean that my dad, who already HAS PD, should avoid pesticides such
as home exterminator chemicals?  Or does it mean that I should warn my
brother and sister, out of concern for possible, very long-term effects of
such exposure on their young children?  Does the study assume long or short
term exposures?

Michael, son of Wayne 70/69/67


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P A N U P S
Pesticide Action Network Updates Service
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Parkinson's Linked to Residential Pesticide Use

August 4, 2000

A recent study of people newly diagnosed with Parkinson's disease
has found that home pesticide use and exposure is associated with an
increased risk of developing the disease. The study, led by Lorene
Nelson, Ph.D., a neuroepidemiologist at Stanford University's School
of Medicine, in Palo Alto, California, is the largest ever of
individuals with newly diagnosed Parkinson's, and the first to show
an association between home pesticide use and the risk of developing
Parkinson's disease. The study's findings were presented in May
2000, at the American Academy of Neurology's 52nd Annual Meeting in
San Diego, and the full report is expected to be released in early
2001.

Nelson and her colleagues questioned 496 people who were first
diagnosed with Parkinson's in 1994 and 1995 about their past use of
pesticides in their homes or gardens. The subjects were each asked
detailed questions about types of pesticides used, frequency of use,
and when they were first exposed to household and garden pesticides.
The researchers also asked subjects about their cigarette, alcohol
and coffee consumption. A control group of 541 people without the
disease were asked the same questions.

When researchers compared the life histories of the subjects and the
control group, they found that people exposed to in-home
insecticides were 70% more likely to develop the disease than those
who had not been exposed. The average amount of time that people
reported being exposed to products in this category was 77 days.
Exposure to garden insecticides carried a 50% increased risk of the
disease, according to the study. Among herbicide users, risk of
developing Parkinson's increased as the number of days that people
were in contact with herbicides accumulated. Respondents who
reported handling or applying those products for up to 30 days were
40% more likely to develop the disease, whereas respondents that
reported higher levels of exposure, an average of 160 days, had a
70% increased risk of developing the disease. Exposure to
fungicides, while linked to other health problems, was not
determined to be a risk factor for Parkinson's disease in this
study.

According to Nelson, damage to nerve cells in a part of the brain
called the basal ganglia and subsequent deficiency in the
neurotransmitter dopamine leads to the balance and movement
difficulties characteristic of Parkinson's disease. People exposed
to chemicals that have a certain affinity to this region of the
brain may be at particular risk for developing the disease, says
Nelson.

Source: Technical Report, Beyond Pesticides/National Coalition
Against the Misuse of Pesticides, Vol. 15, No. 7, July 2000.

Contact: Beyond Pesticides/National Coalition Against the Misuse of
Pesticides, 701 E Street SE, Suite 200, Washington DC 20003; phone
(202) 543-5450; fax (202) 543-4791; .

PANUPS is a weekly email news service providing resource guides and
reporting on pesticide issues that don't always get coverage by the
mainstream media. It's produced by Pesticide Action Network North
America, a non-profit and non-governmental organization working to
advance sustainable alternatives to pesticides worldwide.

You can join our efforts! We gladly accept donations for our work
and all contributions are tax deductible in the United States. Visit
our extensive web site at  to learn more about
getting involved.

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