Re: pd and cd and suicide

[Carole Hercun <grinchcsh@xxxxxxxxx>]

janet-Serotonin and norepinephrine place a major role in
depression, but re: dopamine:
"Some studies have reviewed the hypothesis that dopamine
hypofunction may play a significant role in depressive
illness. D'haenen and Bossuyt reported an increase in D2
receptor density in depressed patients. These studies,
viewed in the context of antidepressant effects reported
with the use of dopamine agonists bromocriptine, piribedil,
and pergolide, further strengthen the hypothesis that the
dopamine system is an important mechanism in at least some
depressed patients. The therapeutic use of stimulants in
selected patients appears to have a growing theoretical and
empirical basis, particularly in view of the limited
dopaminergic effects of most standard antidepressant
medications." -p.513 Textbook of Psychopharmacology
                     The American Psychiatric Press (1998)
And, yes, Schizophrenic patients get depressed. They also
get Parkinsonian side-effects ( an old-fashioned example is
the Thorazine Shuffle) this is not so surprising when you
consider the fact that they are taking meds to limit the
excess dopamine in their brains.  Carole

--- janet paterson <janet313@xxxxxxxxxxx> wrote:
> At 07:36 2000/11/27 -0800, carole wrote:
> >Good morning, janet- Not to negate the psychological
> causes
> >for CD, BUT, dopamine deprivation is well-documented
> >as a physiological cause for depression, and what is PD,
> if
> >not that?    Carole
>
> hi carole
>
> you have told me something i didn't know
> dopamine-deprivation?
> would this not be a direct indicator for the 50%
> incidence of cd in pd?
> how come the idea of the link seems to meet such
> resistance at times
> from both parkies and medicos?
>
> i've understood that serotonin shortage is implicated in
> both cd and pd
> is that your understanding too?
>
> so
> do schizophrenics (an overabundance of dopamine) tend to
> not get cd?
>
> hmmm...
>
> off now more later
>
> jmp
>
> janet paterson, an akinetic rigid subtype parkie
> 53 now /44 dx cd / 43 onset cd /41 dx pd / 37 onset pd
> TEL: 613 256 8340 SMAIL: POBox 171 Almonte Ontario K0A
> 1A0 Canada
> EMAIL: janet313@xxxxxxxxxxx URL:



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