Re: STN DBS, a question

[Hans van der Genugten <genugten@xxxxxxxxxxxxx>]

Hi David,

>> has anyone on this list had a STN DBS after having a bilateral
Pallidotomy Or does someone know of a person who has? If So, What were the
rersults? Were they positive? <<

First a note: I have NOT had this procedure myself.

There have been studies of DBS of the STN, and there is about 5 years (in
Europe) of experience with larger groups of patients with DBS of the STN.

There have been NO studies with patients having a DBS of the STN after a
(bilateral) pallidotomy, but there have been a few individual cases in which
DBS of the STN was performed after a pallidotomy some years before. The
results IN THESE FEW EXPERIMENTAL INDIVIDUAL CASES seem to indicate that a
DBS of the STN, after a previous pallidotomy, has in general the same
benifits, BUT NOT QUITE AS EFFECTIVE as a DBS of the STN would have been
without a previous pallidotomy.

The outcome of DBS of the STN after a pallidotomy is still highly
impredictable, and should IMO for the moment only be considered after a VERY
CAREFUL evaluation of the patient by a VERY EXPERIENCED (in DBS of the STN)
neurologist and neurosurgeon.

Hans.

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