Re: Tremor and PD

[Jorge Romero MD <romero.jorge@xxxxxxxxxxxxxxxx>]

Be careful.

There is no evidence that levodopa is neurotoxic in humans.  The
manufacturers of the dopamine agonists have long been promoting this idea
which has never ben confirmed.

There is no evidence that pramipexole is neuroprotective in humans.  Only
preliminary studies in animals under conditions have even hinted at the
antioxidant qualities of pramipexole.  However, no trials of antioxidants of
any type in humans have shown any clinically relevant neuroprotection.

Do not fall for drug company hype.

Jorge Romero, MD

----- Original Message -----
From: "winddam" <winddam@xxxxxxxxxxx>
To: <PARKINSN@xxxxxxxxxxxxxxxxxxxx>
Sent: Friday, April 05, 2002 2:10 PM
Subject: Re: Tremor and PD


> Dr Jorge, ker
>
> Thank you for your reply.  In fact the propranolol does seem to help my
> husband a bit but he has very low blood pressure so he can't take too
much.
> We shall check out the medication with our GP.  I understand from another
> message I have picked up on PARKINSN that  pramipexole, which I believe is
> "Mirapex"(?), is better than levadopa since it does not accelerate the
> demise of dopamine producing cells, as does levadopa.  However, we
obviously
> have to find a movement disorder specialist and make sure first of the
> diagnosis, and this I shall now do.  I have the feeling that services are
> better in the States, but I suppose this is logical given the greater
> numbers.
>
> Many thanks for your help
>
> dhiso
>
> Julie
> message from winddam@xxxxxxxxxxx
>

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