Re: Need more insight on brother in Dallas Texas

[charlotte A mancuso <mancann@xxxxxxxx>]

On Fri, 28 Jun 2002 22:33:48 -0400 Diane Stevens <claranight@xxxxxxxxx>
writes:
...The fact that your brother's tremor responds to Sinemet
> tells me that he has a brain syndrome that includes damage to the
> substantia nigra.

With all due respect, yes, this "brain syndrome" is called Parkinson's
Disease.  I don't mean to sound sarcastic, but a positive response to
Sinemet is how many neurologist's conclude that a person has PD.  Also,
PD is a result of dopamine-producing brain cells dying in the Substantia
Nigra--that's what PD is.  IMHO, it's not clear to me, from what I've
read about Larry's brother's symptoms, that he has shown Parkinson's
Plus, except perhaps that he has progressed so fast and so severely.

I do agree, though, that he should be evaluated by another neurologist
that specializes in, and is up to date on PD and it's therapies.

Just my two cents worth.

Charlotte Mancuso


On Fri, 28 Jun 2002 22:33:48 -0400 Diane Stevens <claranight@xxxxxxxxx>
writes:
> Dear Larry ,  The fact that your brother's tremor responds to Sinemet
> tells me that he has a brain syndrome that includes damage to the
> substantia nigra. but the other more devastatimg symptoms lead me to
> believe he has what neurologists call a parkinson's plus syndrome or
> perhaps another illness has ocurred on top of the PD  So  I would
> take
> him to a movement disorder specialist as soon as possible.  Contact
> the
> local office of the APDA, NPF or UPF for a referral.  Diane
>
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