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Re: on a causal theory of PD
you write: "If one's heart is beating like a metronome it is an indicator of a serious disease. The same we can see in the case of tremor. Normal spectral curves of the tremor have a wide spectrum. ... The fact that in the case of the PD the spectral curves of the resting tremor demonstrate a sharp peak at 5 Hz together with sharp harmonics at 10 and 20 Hz clearly says: there is something very special. Just in temporal processes. Being a resonance of a mysterious origin." Unless I'm very much mistaken, tremor is abnormal with any rhythm. Charlotte On Sun, 30 Jun 2002 19:56:42 +0000 Vello Reeben <vello_reeben@xxxxxxxxxxx> writes: > Hello Paul, > > you write > > > P.L.:>At first I thought the 'causal theory' thread was someone > having > >fun...but over time it is becoming clear (hah!) that its proponent > is > >serious about the theory...or extraordinarily serious about > pulling >our > legs. In the former case, I would suggest trying to make the point > >without > esoteric formulas and theorem names. > ........ > > With all this in my background, I HAVE NOT THE VAGUEST CONCEPT > ABOUT > >WHICH THIS MAN SPEAKS. > > V.R.: Well, as I have written already, in my first mail I tried to > present > the SPECIFIC CORE of a new hypothesis on the genesis of PD based on > a > rhythms-based approach. I am sorry that the specific language needed > for > that made difficult to catch the main idea. > > Actually the MAIN IDEA is not complicated at all: all the normal > physiological processes are rhythmical, in digestive system, in > circulatory > system, in nervous system. Our heart beats rhythmically, we breathe > rhythmically. > By means of various scientific instruments we can record the > oscillating > TIME SEQUENCIES in all these parameters, computers and mathematical > algorithms allow us to find out whether there exist certain > PERIODICALLY > REPEATING EVENTS in them. The latter mentioned events are called > RHYTHMS or > CYCLES or PERIODS (or REAL DURATIONS by Henri Bergson) or with a > predicative > also as WAVES (the EEG alpha-wave). > The information about rhythms is presented as full SPECTRAL CURVES > in > co-ordinates intensity-time or intensity-frequency, or, as usually > in > medicine, as simplified BAR CURVES or numerical BAR DATA showing us > how > many EEG waves fall into a typical alpha zone, beta zone etc. > If an event repeats in a way as the metronome beats the spectral > curve > will show us only a narrow peak. It shows then that there is a sharp > resonance in the system. > In normal physiology all the rhythms are interlinked with each > other and modulate each other so that any sharp resonance is not > seen. > If one's heart is beating like a metronome it is an indicator of a > serious > disease. > The same we can see in the case of tremor. Normal spectral curves of > the > tremor have a wide spectrum. Only in the case of a strong fatigue, > like it > is noticed in overtired pilots and drivers case, one can see a sharp > tremor > spectrum and that for a short time. > The fact that in the case of the PD the spectral curves of the > resting > tremor demonstrate a sharp peak at 5 Hz together with sharp > harmonics at 10 > and 20 Hz clearly says: there is something very special. Just in > temporal > processes. Being a resonance of a mysterious origin. > So we have real reasons to think that just a rhythm-based approach > is > adequate for a study of this special phenomenon. > > Thus, general aspects of the core of the present causal theory can > easily > be described. > > However, the next step needs already some digging into our NEW > GENERAL theory of natural rhythms. > Here we have to tell you that our turn to a theory of the > genesis of > the Parkinson's disease did not appear on an empty place, has not > been > accidental: > - our biophysical lab has a 40 years experience in the study of > various > physiological rhythms, especially circulatory rhythms, > - in our desire to understand the biophysical mechanisms of human > physiological rhythms we discovered that they well fit into the > great > system of environmental, climatic, astronomic rhythms which all > happened > to be tied with the GALACTIC YEAR, > - we discovered that a great part of all the rhythms discovered in > variuos sciences up to now can be described as SPECIAL INTEGER parts > of > the galactic year T(0), > - we discovered that an integer part of the galactic year T(0)/N > obtains a > status of an essential natural rhythm in the case > 1) when it enables MAXIMAL TIES with all the other such integer > parts, > when it can go into the "green versatile highway" of the evolution, > mathematically when N is a highly composite number by Ramanujan > (h.c.n); a > nice example for understanding this criterion of informational > optimum is a > timetable of city buses: when the full period of circulation is a > Ramanujan > number (in minutes) we have maximum number of versions to regulate > the > frequency of traffic by means of the number of buses on line keeping > all the > time a convenient full-minute timetable; BTW, we have got from our > ancestors > just such system of time: 12, 24, 60, 360, in Plato's ideal town was > just > 5040 inhabitants; > 2) when this ramanujanian N is at the same time a near-quadratic > number (N > = a^2 +- epsilon); this criterion is the same as in > Balmer-Rydberg-Bohr > theory of the spectral lines of the hydrogen atom; there are only > two N=a^2 > type Ramanujan numbers (4, 36) and only eight > N=a^2-1 type numbers; all of them give us important natural rhythms; > the > domain number of PD-rhythms we are pointing to is also a N=a^2-1 > number but > with a deviation from the Ramanujan optimum 2.65 times, > - in our attempts to understand the nature of the 11 sec rhythm of > blood > pressure and of vasomotor system, putting question why it is so > different > from the heart rate rhythm and its variations, we paid attention to > such > GROUPS of natural rhythms which are described by h.c.n.-s with > general > highest prime divisor p(max); it appears that the main physiological > rhythms > of mammals are described by the following six groups of h.c.n.-s > where the > N(19), N(23) and N(31) groups give us CLOSE-SYSTEM (mathematically > imaginary) rhythms connected with compact structures (heart, > lung,..) and > N(29), N(37) and N(41) groups give us OPEN-SYSTEM (mathematically > real) > rhythms connected with distributed structures (arterioles, > erythrocytes, > neurons); these ideal ramanujanian rhythm groups are in the > following range > of time: > > N(19) - Im: 107 d - 6.13 h temperature, metabolism > N(23) - Im: 1.17 d - 4.00 min digestive tract > N(29) - Re: 11.6 min - 8.27 s vasomotor system > N(31) - Im: 22.4 s - 11.2 Hz heart, breathing > N(37) - Re: 11.6 Hz - 1390 Hz brain, phonetics, music > N(41) - Re: 474 Hz - 56.8 kHz phonetics, music > > Physiological tremor is connected with N(37) brain waves but > the > PD-rhythms belong to the N(31) group of CLOSED-SYSTEM rhythms! Just > that > circumstance is important in understanding such facts that the > PD-rhythms > form in a LOCAL area of the brain CLOSED zones with a continuous > irritation, > that they create a phenomenon of movement freezing, a need for a > threshold > overcoming, in various muscles a phenomenon of (closed) rigidity. > > The phenomenon of bradykinesia, of movement slowness is understood > in our > model so: at the beginning the quantum jump to alien rhythm happens > at EEG > theta wave, then the resting tremor is the main symptom of PD, at > this > frequency the deviation of the PD-rhythm from the optimum is 3.69 > times. > Now look, the most less deviation, 2.39 times, has a NINE TIMES > slower > PD-rhythm which has a period 1.56 sec instead of 5.76 Hz. Thus, in > the > course of time it is energetically useful to overcome to this slow > rhythm. > The phenomenon of handwriting change, at first still clear but > very small, > is understood so: normally the handwriting is learned under the > quadratic > rhythms (as in handwriting the main figure is an ellipse together > with its > translation shifts) which are connected with the quantum prime > dividers 2^n. > After the quantum jump there appear smaller sub-rhythms of the 2^n > type > which seem to cause such a very peculiar phenomenon. > > Vello Reeben > > >From: Paul Lauer <PHL1037@xxxxxxx> > >Reply-To: Parkinson's Information Exchange Network > ><PARKINSN@xxxxxxxxxxxxxxxxxxxx> > >To: PARKINSN@xxxxxxxxxxxxxxxxxxxx > >Subject: Re: on a causal theory of PD > >Date: Sun, 23 Jun 2002 22:45:22 EDT > > > >I believe at the time I defended Jan Abas' theories with the > admonition to > >the naysayers that whatever works for him is great whether real or > >imagined. > >But to call it or its tenets 'science' and clothe it in an > unintelligible > >litany of scientific sounding claptrap disguised with and wrapped > around > >terms which are equated with magic (I had to search google for some > of > >them). > > > >At first I thought the 'causal theory' thread was someone having > >fun...but > >over time it is becoming clear (hah!) that its proponent is > >serious about > >the theory...or extraordinarily serious about pulling >our legs. In > the > >former case, I would suggest trying to make the point >without > esoteric > >formulas and theorem names. This is a PD list and not >a seminar in > >Gaussian mathematics (I used that term because it sprang >to mind. > I'm sure > >it's not applicable to the proponent's argument but >for me it is > equally > >obscure). I am reasonably literate. I have a BSCE >in Civil > Engineering, a > >license to practice >Professional Engineering >in NY and CT, an MBA > and I > >am AbD (academic joke lingo for a PhD "all >but dissertation" > meaning > >really that the PhD was never completed). I >read the New York > Times and > >Wall Street Journal daily. OK, so > >not cover to cover but enough to consider myself reasonably well > >informed > >as a result. I am a graduate of the US Army Command and >General > Staff > >College,The National Defense University Security >Management > Course, The > >Army War College (like getting a PhD in War >Management) and a > member of > >the Beta Gamma Sigma Honor Society. A >Million years ago I was a > childhood > >member of Mensa, I used to play >chess with three people > simultaneously at > >Cafe Rienzi in Greenwich >Village until three in the morning and > then go > >play rubber bridge > >for three cents a point which in the 1960s was an expensive game. > With >all > >this in my background, I HAVE NOT THE VAGUEST CONCEPT ABOUT WHICH > >THIS MAN > >SPEAKS. > > > >Paul h. 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