Re: Levodopa induces free radical formation?

[ERVIN J MCCARTHY <ERVIN_MCCARTHY@xxxxxxxxxxx>]

Can anyone give me and explanation for the different designations of
Sinemet.
I see all kinds of different figures like, 25/100, 30/100, 50/100, and all
kinds of other numbers.  I guess I'm still confused.  Thanks in advance for
the help.
ERVIN_MCCARTHY@xxxxxxxxxxx
-----Original Message-----
From: J. R. Bruman <jrbruman@xxxxxxxxxxxxx>
To: Multiple recipients of list PARKINSN <PARKINSN@xxxxxxxxxxxxxxxxxxxx>
Date: Sunday, July 26, 1998 5:03 PM
Subject: Re: Levodopa induces free radical formation?


>Phil Tompkins wrote:
>> 1.  This is a side-effect you don't read of in the monographs.  I
>> haven't seen this discusssed on the list either, nor do I believe
>> that neurologists mention this to their patients.  Why? Wouldn't you
>> want to know all the risks?  Is levodopa toxicity being kept a
>> secret, or is not enough known about it to say for sure that it is a
>> real problem?
>
>It's a long-standing unsettled debate among researchers. Very briefly,
>effects on cultured cells in a petri dish don't seem to agree with
>numerous clinical findings. I've reviewed a number of research papers
>on the subject in the monthly Current Science Reviews that appears
>here. Cheers,
>Joe
>--
>J. R. Bruman   (818) 789-3694
>3527 Cody Road
>Sherman Oaks, CA 91403-5013