Sleep benefit

["J. R. Bruman" <jrbruman@xxxxxxxxxxxxx>]

Here are a couple of items from my CSR files:

Merello M et al; Mov Disord 1997;12:506-508:
By a questionnaire survey of 312 PD patients, they found that about
half feel better for an hour or more after sleeping, to the degree
that they could skip or delay the morning dose of levodopa.

Hogl B et al; Neur 1998;50:1332-1339:
Some PD patients feel better and have fewer motor symptoms on
waking in the morning, despite the prolonged deprivation of
levodopa, while others do not. To study this, they gave motor
tests to 10 patients with sleep benefit and 10 without. The
former group, as expected, did better on the morning motor tests
but was more susceptible to "off" spells between levodopa doses.

Cheers,
Joe
--
J. R. Bruman   (818) 789-3694
3527 Cody Road
Sherman Oaks, CA 91403-5013