[no subject]

[Rhonda <rsavitch@xxxxxxxxxx>]

Hi.  This is my first communication as a new member of this list or any 
internet exchange.  I am 47 years old and was diagnosed with Parkinson's about 
one year ago, after two years of uncertain diagnoses of multiple sclerosis and 
primary lateral sclerosis.  I have no tremor, and the symptoms of 
Parkinson's--muscle rigidity, balance problems, slow movement, etc.--currently 
affect the left side of my body more than the right.  

I presently use Sinemet 25/100 five times daily in combination (within the last 
few months) with 1 gram Mirapex three times daily.  I'm not yet sure what 
effect, if any, the Mirapex provides, although the effect of the Sinemet is 
certainly dramatic.  Unfortunately, I have developed "variable response" 
syndrome with respect to the Sinemet.  My current physician, a neurologist 
whose subspecialty is Parkinson's) tells me that it would have been preferable 
not to have begun my treatment with Sinemet because of the possibility of 
developing this very syndrome--hence the experiment with Mirapex.  (The Sinemet 
was originally prescribed by my current doctor's colleague, a well-respected 
neurologist whose subspecialty is multiple sclerosis.)  

I am a lawyer whose focus is civil litigation.  In order to function during the 
day, I find that I need to use the Sinemet at no less than 3.5 hour intervals, 
which means significantly less function at night.   I also find that I need to 
rest for about 30 minutes before each dose of Sinemet, which can be 
problematic.   All of this makes professional life difficult.  It is also a 
nuisance at home, where evenings are usually devoted to activities with my 
husband.

Any thoughts for a newcomer about managing what must be a familiar scenario to 
most of you?  Sorry for the long initial message and thanks in advance for your 
time.

Rhonda