Fwd: Q: PD-Medication - Gener...

[Paul Potter <Janpotter@xxxxxxx>]

I asked a former colleague to answer this question and am passing on her
answer. Medical librarians are great!

aloha to all. Janpotter@xxxxxxx for Paul
---------------------
Forwarded message:
From: heidi@xxxxxxxxxxxxxxxxxxxx (Heidi's Mac)
To: Janpotter@xxxxxxx
CC: hh@xxxxxxxxxxxxxxxxxxxx
Date: 95-03-30 16:33:26 EST

Hi,

I was able to pop into medline and determine the generic
for the following--  I included additional info re: broader
terms and the scope notes when available.

Hope you find this useful.

Best wishes
always,  Heidi

Naprosyn = naproxen

BROADER HEADINGS:  (all have narrower headings)
    1.22 Anti-Inflammatory Agents, Non-Steroidal.               4,872
citations
    1.23 Gout Suppressants.                                        12
citations
    1.24 Cyclooxygenase Inhibitors.                               499
citations
    1.25 Naphthaleneacetic Acids.                                  35
citations

TREE NO.: D4.615.638.472.450    D8.373.310.500    D16.850.15.50.590
          D17.25.30.550    D17.50.30.550    D17.50.337.550

PREVIOUS INDEXING: Methyl Ethers (73-74)
                   Naphthalenes (72-74)
                   Propionates (72-74)

SCOPE NOTES: 2-(6-Methoxy-2-naphthyl)propionic acid. An anti-inflammatory
agent
    with analgesic and antipyretic properties. Both the acid and its sodium
    salt are used in the treatment of rheumatoid arthritis and other
rheumatic
    or musculoskeletal disorders, dysmenorrhea, and acute gout.

Sinemet/Sinamet (sp?) = carbidopa

BROADER HEADINGS:  (all have narrower headings)
    1.15 Antiparkinson Agents.                                    351
citations
    1.16 Methyldopa.                                              155
citations
    1.17 Dopamine Neuron Agents (Non MeSH)                          0
citations
    1.18 Enzyme Inhibitors.                                       674
citations
    1.19 Hydrazines.                                              552
citations

TREE NO.: D2.92.311.242.538.200    D2.442.200    D8.373.210
          D14.100.150.600.142    D15.90.50.150

USED FOR: Methyldopahydrazine.
          MK-485.
          MK-486.

PREVIOUS INDEXING: Dopa (72-74)
                   Hydrazines (72-74)
                   Methyldopa (72-74)

SCOPE NOTES: A peripheral inhibitor of DOPA DECARBOXYLASE. It is given in
    parkinsonism along with LEVODOPA to inhibit the conversion of levodopa to
    dopamine in the periphery, thereby reducing the peripheral adverse
effects,
    increasing the amount of levodopa that reaches the central nervous
system,
    and reducing the dose needed. It has no antiparkinson actions when given
    alone.

Parlodel = bromocriptine

USED FOR: Bromocryptin.
          2-Bromoergocryptine.

PREVIOUS INDEXING: Ergot Alkaloids (66-74)

SCOPE NOTES: A semisynthetic ergot alkaloid that is a dopamine D2 agonist. It
    suppresses prolactin secretion and is used to treat amenorrhea,
    galactorrhea, and female infertility, and has been proposed for Parkinson
    disease.

Eldepryl = selegiline

BROADER HEADINGS:  (all have narrower headings)
    1.18 Antiparkinson Agents.                                    351
citations
    1.19 Phenethylamines.                                         548
citations
    1.20 Monoamine Oxidase Inhibitors.                            866
citations

TREE NO.: D2.92.471.683.915    D8.373.616.900    D15.90.50.800

USED FOR: Deprenalin.
          Deprenil.
          Deprenyl.

PREVIOUS INDEXING: Monoamine Oxidase Inhibitors (66-78)
                   Phenethylamines (66-78)

SCOPE NOTES: (R)-N,alpha-Dimethyl-N-2-propynylbenzeneethanamine. A selective,
    irreversible inhibitor of Type B monoamine oxidase. It is used in newly
    diagnosed patients with Parkinson's disease. It may slow progression of
the
    clinical disease and delay the requirement for levodopa therapy. It also
    may be given with levodopa upon onset of disability. (From AMA Drug
    Evaluations Annual, 1994, p.385) The compound without isomeric
designation
    is deprenyl.

Pramipexole = 104632-26-0 (pramipexol)

Permax = Pergolide (Permax, LY127809, CAS 66104-23-2) a dopamine agonist for
    the treatment of Parkinson's disease.


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