Re: Permax and Psychosis

[Charles Meyer <meyerct@xxxxxxxxxxxxxxxx>]

Monica

Virtually all of the dopamine agonist medications eg Permax, & Parlodel as
well as other drugs like Sinemet and Eldepryl which increase dopamine in the
synapse are associated at times with delusions and hallucinations in a
portion of the PD population.  If he absolutely needs the offending
medication sometimes Clozaril can be added although treatment of this is not
an FDA approved indication it is widely used-  although there are some very
real risks.  Unlike most of the other neuroleptic medications it does not
(usually) worsen PD symptoms and in some individuals is actually theraputic
for PD.

Good luck,

Charlie



  My dad had a severe psychotic episode a few years ago, which lasted for
>  days.  He was taken off Permax then, and never resumed dosage until
>  recently; he built up from a small amount.  A week or so ago, he had
>  another hallucination.  He says he felt as if he was in a rocket ship
>  about to crash.  He stopped Permax, and is very wary of it.  Any similar
>  stoires?
>
>  Monica
>
>
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 Charles T. Meyer
 Madison, WI

meyerct@xxxxxxxxxxxxxxxx
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