More Pesticide and Parkinson's Disease Info

[Wendy Tebay <RosaBosa@xxxxxxx>]

Here's another abstract from Medline/Toxline possibly linking pesticides
(including the infamous DDT) and Parkinson's Disease.

Wendy Tebay
RosaBosa@xxxxxxx
*****************************************

3
AU  - FLEMING L
AU  - MANN JB
AU  - BEAN J
AU  - BRIGGLE T
AU  - SANCHEZ-RAMOS JR
TI  - Parkinson's disease and brain levels of organochlorine
      pesticides.
SI  - BIOSIS/94/25827
SO  - ANNALS OF NEUROLOGY; 36 (1). 1994. 100-103.
AB  - BIOSIS  COPYRIGHT: BIOL ABS.  Epidemiological studies have
      suggested an etiologic relationship between pesticide exposure
      and Parkinson's disease (PD). Organochlorine pesticides were
      assayed in postmortem brain samples from 20 PD, 7 Alzheimer's
      disease (AD), and 14 nonneurological control cases. The three
      groups were similar in age at death, sex, and demographic
      variables. Only two of 16 pesticide residues screened were
      detected. A long-lasting residue of DDT (pp-DDE) was found in the
      majority of cases of PD and AD, as well  as in all the control
      cases; pp-DDT was significantly more likely to be found in AD
      controls than the PD cases (Fisher's exact two-tailed, p = 0.04).
      Dieldrin was detected in 6 of 20 PD brains, 1 of 7 AD, and in
      none of 14 control samples. Despite the relatively small number
      of brains assayed, the association between Dieldrin and the
      diagnosis of PD was highly significant (P = 0.03). Dieldrin, a
      lipid-soluble, long-lasting mitochondrial poison, should be
      investigated as a potential etiological  agent of Parkinsonism.
MH  - BEHAVIOR
MH  - HUMAN
MH  - BIOCHEMISTRY
MH  - NERVOUS SYSTEM/PHYSIOLOGY/METABOLISM
MH  - NERVOUS SYSTEM DISEASES/*PATHOLOGY
MH  - MENTAL DISORDERS/THERAPY/PATHOLOGY
MH  - PSYCHOPATHOLOGY
MH  - ENVIRONMENTAL POLLUTANTS/POISONING
MH  - OCCUPATIONAL DISEASES
MH  - HERBICIDES
MH  - PEST CONTROL/METHODS
MH  - PESTICIDES
MH  - ARACHNIDA
MH  - ENTOMOLOGY/ECONOMICS
MH  - INSECTICIDES
MH  - PEST CONTROL/METHODS
MH  - PESTICIDES
MH  - HOMINIDAE
RN  - 53469-21-9; 27304-13-8; 12789-03-6; 12674-11-2; 12672-29-6;
      11097-69-1; 11096-82-5; 3424-82-6; 1024-57-3; 789-02-6; 309-00-2;
      115-32-2; 76-44-8; 72-56-0; 72-55-9; 72-20-8; 60-57-1; 58-89-9;
      50-29-3