Electrical Stimulation

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Electrical Stimulation

Subject: Electrical Stimulation
From: Ken Aidekman <Quabitt@xxxxxxx>
Date: Wed, 6 Dec 1995 12:23:40 -0500
Reply-to: Parkinson's Disease - Information Exchange Network <PARKINSN@xxxxxxxxxxxxxxx>
Sender: Parkinson's Disease - Information Exchange Network <PARKINSN@xxxxxxxxxxxxxxx>

It is my understanding that electical stimulation of the globus pallidus is
used to knock out the activity of neurons in that region without destroying
them.  Low levels of stimulation increase the rate of neuronal firing, but
higher levels overload the cells to the point that they can no longer fire.
 This decreases the overactivity in the region which is associated with
tremor and dyskinesia in PD.  Hopefully no long term damage is done in the
process and treatment can be modulated to correspond to symptoms.

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